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Murine Pancreatic Adenocarcinoma Dampens SHIP-1 Expression and Alters MDSC Homeostasis and Function

BACKGROUND: Pancreatic cancer is one of the most aggressive cancers, with tumor-induced myeloid-derived suppressor cells (MDSC) contributing to its pathogenesis and ineffective therapies. In response to cytokine/chemokine receptor activation, src homology 2 domain-containing inositol 5′-phosphatase-...

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Detalles Bibliográficos
Autores principales:	Pilon-Thomas, Shari, Nelson, Nadine, Vohra, Nasreen, Jerald, Maya, Pendleton, Laura, Szekeres, Karoly, Ghansah, Tomar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222660/ https://www.ncbi.nlm.nih.gov/pubmed/22132131 http://dx.doi.org/10.1371/journal.pone.0027729

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