The Heritability of Amyotrophic Lateral Sclerosis in a Clinically Ascertained United States Research Registry

BACKGROUND: The genetic basis of amyotrophic lateral sclerosis (ALS) is not entirely clear. While there are families with rare highly penetrant mutations in Cu/Zn superoxide dismutase 1 and several other genes that cause apparent Mendelian inheritance of the disease, most ALS occurs in families with...

Descripción completa

Detalles Bibliográficos
Autores principales: Wingo, Thomas S., Cutler, David J., Yarab, Nicole, Kelly, Crystal M., Glass, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222666/
https://www.ncbi.nlm.nih.gov/pubmed/22132186
http://dx.doi.org/10.1371/journal.pone.0027985

Ejemplares similares

Ejemplares similares