Following Nerve Injury Neuregulin-1 Drives Microglial Proliferation and Neuropathic Pain via the MEK/ERK Pathway

Following peripheral nerve injury microglia accumulate within the spinal cord and adopt a proinflammatory phenotype a process which contributes to the development of neuropathic pain. We have recently shown that neuregulin-1, a growth factor released following nerve injury, activates erbB 2, 3, and...

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Detalles Bibliográficos
Autores principales: Calvo, Margarita, Zhu, Ning, Grist, John, Ma, Zhenzhong, Loeb, Jeffrey A, Bennett, David L H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222694/
https://www.ncbi.nlm.nih.gov/pubmed/21319222
http://dx.doi.org/10.1002/glia.21124

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