Cargando…
The ACT-ONE trial, a multicentre, randomised, double-blind, placebo-controlled, dose-finding study of the anabolic/catabolic transforming agent, MT-102 in subjects with cachexia related to stage III and IV non-small cell lung cancer and colorectal cancer: study design
AIMS: Cachexia, the wasting disorder associated with a wide range of serious illnesses including cancer, is a major cause of morbidity and mortality. There is currently no widely approved therapeutic agent for treating or preventing cancer-associated cachexia. Colorectal cancer and non-small cell lu...
Autores principales: | Stewart Coats, Andrew J., Srinivasan, Venkatesan, Surendran, Jayaraman, Chiramana, Haritha, Vangipuram, Shankar R. K. G., Bhatt, Nirajkumar N., Jain, Minish, Shah, Sandip, Ali, Irfhan A. B. H., Fuang, Ho G., Hassan, Mohammed Z. M., Beadle, John, Tilson, Julia, Kirwan, Bridget-Anne, Anker, Stefan D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222831/ https://www.ncbi.nlm.nih.gov/pubmed/22207908 http://dx.doi.org/10.1007/s13539-011-0046-2 |
Ejemplares similares
-
Espindolol for the treatment and prevention of cachexia in patients with stage III/IV non‐small cell lung cancer or colorectal cancer: a randomized, double‐blind, placebo‐controlled, international multicentre phase II study (the ACT‐ONE trial)
por: Stewart Coats, Andrew J., et al.
Publicado: (2016) -
The anabolic catabolic transforming agent (ACTA) espindolol increases muscle mass and decreases fat mass in old rats
por: Pötsch, Mareike S., et al.
Publicado: (2013) -
MT‐102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia
por: Pötsch, Mareike S., et al.
Publicado: (2020) -
The Use of Anabolic Agents in Catabolic States
por: Demling, Robert
Publicado: (2007) -
Higher serum phosphorus is associated with catabolic/anabolic imbalance in heart failure
por: Rozentryt, Piotr, et al.
Publicado: (2015)