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Parallel screening of FDA-approved antineoplastic drugs for identifying sensitizers of TRAIL-induced apoptosis in cancer cells

BACKGROUND: Tumor Necrosis Factor-α Related Apoptosis Inducing Ligand (TRAIL) and agonistic antibodies to death receptor 4 and 5 are promising candidates for cancer therapy due to their ability to induce apoptosis selectively in a variety of human cancer cells, while demonstrating little cytotoxicit...

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Detalles Bibliográficos
Autores principales:	Taylor, David J, Parsons, Christine E, Han, Haiyong, Jayaraman, Arul, Rege, Kaushal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223153/ https://www.ncbi.nlm.nih.gov/pubmed/22044796 http://dx.doi.org/10.1186/1471-2407-11-470

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