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Glucocorticoid Regulation of SLIT/ROBO Tumour Suppressor Genes in the Ovarian Surface Epithelium and Ovarian Cancer Cells

The three SLIT ligands and their four ROBO receptors have fundamental roles in mammalian development by promoting apoptosis and repulsing aberrant cell migration. SLITs and ROBOs have emerged as candidate tumour suppressor genes whose expression is inhibited in a variety of epithelial tumours. We de...

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Detalles Bibliográficos
Autores principales: Dickinson, Rachel E., Fegan, K. Scott, Ren, Xia, Hillier, Stephen G., Duncan, W. Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223191/
https://www.ncbi.nlm.nih.gov/pubmed/22132142
http://dx.doi.org/10.1371/journal.pone.0027792