Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β

BACKGROUND: Microglia and astrocytes respond to homeostatic disturbances with profound changes of gene expression. This response, known as glial activation or neuroinflammation, can be detrimental to the surrounding tissue. The transcription factor CCAAT/enhancer binding protein β (C/EBPβ) is an imp...

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Detalles Bibliográficos
Autores principales: Straccia, Marco, Gresa-Arribas, Núria, Dentesano, Guido, Ejarque-Ortiz, Aroa, Tusell, Josep M, Serratosa, Joan, Solà, Carme, Saura, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223504/
https://www.ncbi.nlm.nih.gov/pubmed/22074460
http://dx.doi.org/10.1186/1742-2094-8-156

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