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Involvement of DNA ligase III and ribonuclease H1 in mitochondrial DNA replication in cultured human cells

Recent evidence suggests that coupled leading and lagging strand DNA synthesis operates in mammalian mitochondrial DNA (mtDNA) replication, but the factors involved in lagging strand synthesis are largely uncharacterised. We investigated the effect of knockdown of the candidate proteins in cultured...

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Detalles Bibliográficos
Autores principales: Ruhanen, Heini, Ushakov, Kathy, Yasukawa, Takehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223524/
https://www.ncbi.nlm.nih.gov/pubmed/21878356
http://dx.doi.org/10.1016/j.bbamcr.2011.08.008