TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

TNF receptor 1 signaling induces NF-κB activation and necroptosis in L929 cells. We previously reported that cellular inhibitor of apoptosis protein-mediated receptor-interacting protein 1 (RIP1) ubiquitination acts as a cytoprotective mechanism, whereas knockdown of cylindromatosis, a RIP1-deubiqui...

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Detalles Bibliográficos
Autores principales: Vanlangenakker, N, Bertrand, M J M, Bogaert, P, Vandenabeele, P, Vanden Berghe, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223695/
https://www.ncbi.nlm.nih.gov/pubmed/22089168
http://dx.doi.org/10.1038/cddis.2011.111

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