Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes

Diabetes is associated with the death and dysfunction of insulin-producing pancreatic β-cells. In other systems, Musashi genes regulate cell fate via Notch signaling, which we recently showed regulates β-cell survival. Here we show for the first time that human and mouse adult islet cells express mR...

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Detalles Bibliográficos
Autores principales: Szabat, M, Kalynyak, T B, Lim, G E, Chu, K Y, Yang, Y H, Asadi, A, Gage, B K, Ao, Z, Warnock, G L, Piret, J M, Kieffer, T J, Johnson, J D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223700/
https://www.ncbi.nlm.nih.gov/pubmed/22113197
http://dx.doi.org/10.1038/cddis.2011.119

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