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Specificity protein, Sp1-mediated increased expression of Prdx6 as a curcumin-induced antioxidant defense in lens epithelial cells against oxidative stress

Peroxiredoxin 6 (Prdx6) is a pleiotropic oxidative stress-response protein that defends cells against reactive oxygen species (ROS)-induced damage. Curcumin, a naturally occurring agent, has diversified beneficial roles including cytoprotection. Using human lens epithelial cells (hLECs) and Prdx6-de...

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Detalles Bibliográficos
Autores principales: Chhunchha, B, Fatma, N, Bhargavan, B, Kubo, E, Kumar, A, Singh, D P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223701/
https://www.ncbi.nlm.nih.gov/pubmed/22113199
http://dx.doi.org/10.1038/cddis.2011.121