Detection of methylation in the CpG islands of the p16INK4A, RASSF 1A and methylguanine methyltransferase gene promoters in pancreatic adenocarcinoma

Pancreatic cancer consists of an accumulation of genetic and epigenetic alterations. Recently, aberrant methylation of CpG islands of cancer-related genes has emerged as an important epigenetic mechanism of their transcriptional dysregulation during tumour development [1]. Therefore, new diagnostic...

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Detalles Bibliográficos
Autores principales: Paikos, D, Stravoravdi, P, Voyatzi, S, Boukovinas, I, Papakotoulas, P, Kiziridou, A, Sibilidis, G, Stergiou, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2009
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223988/
https://www.ncbi.nlm.nih.gov/pubmed/22276000
http://dx.doi.org/10.3332/ecancer.2009.131

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