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Denis Burkitt and the African lymphoma

Burkitt lymphoma has provided a model for the understanding of the epidemiology, the molecular abnormalities that induce tumours, and the treatment of other lymphomas. It is important to remember that the early phases of this work were conducted in Africa where today, unfortunately, the disease usua...

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Autor principal: Magrath, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224008/
https://www.ncbi.nlm.nih.gov/pubmed/22276020
http://dx.doi.org/10.3332/ecancer.2009.159
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author Magrath, I
author_facet Magrath, I
author_sort Magrath, I
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description Burkitt lymphoma has provided a model for the understanding of the epidemiology, the molecular abnormalities that induce tumours, and the treatment of other lymphomas. It is important to remember that the early phases of this work were conducted in Africa where today, unfortunately, the disease usually results in death because of limited resources, even though most children in more developed countries are cured. This must be changed. In addition, it is time to re-explore, with modern techniques, some of the questions that were raised some 50 years ago shortly after Burkitt’s first description, as well as new questions that can be asked only in the light of modern understanding of the immune system and the molecular basis of tumor development. The African lymphoma has taught us much, but there is a great deal still to be learned.
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spelling pubmed-32240082012-01-24 Denis Burkitt and the African lymphoma Magrath, I Ecancermedicalscience Research Article Burkitt lymphoma has provided a model for the understanding of the epidemiology, the molecular abnormalities that induce tumours, and the treatment of other lymphomas. It is important to remember that the early phases of this work were conducted in Africa where today, unfortunately, the disease usually results in death because of limited resources, even though most children in more developed countries are cured. This must be changed. In addition, it is time to re-explore, with modern techniques, some of the questions that were raised some 50 years ago shortly after Burkitt’s first description, as well as new questions that can be asked only in the light of modern understanding of the immune system and the molecular basis of tumor development. The African lymphoma has taught us much, but there is a great deal still to be learned. Cancer Intelligence 2009-09-30 /pmc/articles/PMC3224008/ /pubmed/22276020 http://dx.doi.org/10.3332/ecancer.2009.159 Text en © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Magrath, I
Denis Burkitt and the African lymphoma
title Denis Burkitt and the African lymphoma
title_full Denis Burkitt and the African lymphoma
title_fullStr Denis Burkitt and the African lymphoma
title_full_unstemmed Denis Burkitt and the African lymphoma
title_short Denis Burkitt and the African lymphoma
title_sort denis burkitt and the african lymphoma
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224008/
https://www.ncbi.nlm.nih.gov/pubmed/22276020
http://dx.doi.org/10.3332/ecancer.2009.159
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