Cell–cell fusion as a potential target in cancer therapy

In the fight against cancer, new and more specific targets are needed. Here, we offer an example of a potential target that has not been widely studied, namely the syncytin protein. Syncytin is expressed mainly in the human placenta and is implicated in placental syncytiotrophoblast cell fusion. Not...

Descripción completa

Detalles Bibliográficos
Autores principales: Gasent Blesa, JM, Candel, VA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2009
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224012/
https://www.ncbi.nlm.nih.gov/pubmed/22276010
http://dx.doi.org/10.3332/ecancer.2009.145
_version_ 1782217334348316672
author Gasent Blesa, JM
Candel, VA
author_facet Gasent Blesa, JM
Candel, VA
author_sort Gasent Blesa, JM
collection PubMed
description In the fight against cancer, new and more specific targets are needed. Here, we offer an example of a potential target that has not been widely studied, namely the syncytin protein. Syncytin is expressed mainly in the human placenta and is implicated in placental syncytiotrophoblast cell fusion. Not much is known about the role of syncytin in cancer, but the existing data call for more intense research. Its retroviral origin and particular tissue distribution make syncytin an interesting potential target in cancer therapy.
format Online
Article
Text
id pubmed-3224012
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher Cancer Intelligence
record_format MEDLINE/PubMed
spelling pubmed-32240122012-01-24 Cell–cell fusion as a potential target in cancer therapy Gasent Blesa, JM Candel, VA Ecancermedicalscience Reviews In the fight against cancer, new and more specific targets are needed. Here, we offer an example of a potential target that has not been widely studied, namely the syncytin protein. Syncytin is expressed mainly in the human placenta and is implicated in placental syncytiotrophoblast cell fusion. Not much is known about the role of syncytin in cancer, but the existing data call for more intense research. Its retroviral origin and particular tissue distribution make syncytin an interesting potential target in cancer therapy. Cancer Intelligence 2009-08-06 /pmc/articles/PMC3224012/ /pubmed/22276010 http://dx.doi.org/10.3332/ecancer.2009.145 Text en © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Gasent Blesa, JM
Candel, VA
Cell–cell fusion as a potential target in cancer therapy
title Cell–cell fusion as a potential target in cancer therapy
title_full Cell–cell fusion as a potential target in cancer therapy
title_fullStr Cell–cell fusion as a potential target in cancer therapy
title_full_unstemmed Cell–cell fusion as a potential target in cancer therapy
title_short Cell–cell fusion as a potential target in cancer therapy
title_sort cell–cell fusion as a potential target in cancer therapy
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224012/
https://www.ncbi.nlm.nih.gov/pubmed/22276010
http://dx.doi.org/10.3332/ecancer.2009.145
work_keys_str_mv AT gasentblesajm cellcellfusionasapotentialtargetincancertherapy
AT candelva cellcellfusionasapotentialtargetincancertherapy

Ejemplares similares