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TRPC1 transcript variants, inefficient nonsense-mediated decay and low up-frameshift-1 in vascular smooth muscle cells

BACKGROUND: Transient Receptor Potential Canonical 1 (TRPC1) is a widely-expressed mammalian cationic channel with functional effects that include stimulation of cardiovascular remodelling. The initial aim of this study was to investigate variation in TRPC1-encoding gene transcripts. RESULTS: Extens...

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Detalles Bibliográficos
Autores principales: Dedman, Alexandra M, Majeed, Yasser, Tumova, Sarka, Zeng, Fanning, Kumar, Bhaskar, Munsch, Christopher, Bateson, Alan N, Wittmann, Jürgen, Jäck, Hans-Martin, Porter, Karen E, Beech, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224110/
https://www.ncbi.nlm.nih.gov/pubmed/21749700
http://dx.doi.org/10.1186/1471-2199-12-30