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Bacterial membrane activity of α-peptide/β-peptoid chimeras: Influence of amino acid composition and chain length on the activity against different bacterial strains

BACKGROUND: Characterization and use of antimicrobial peptides (AMPs) requires that their mode of action is determined. The interaction of membrane-active peptides with their target is often established using model membranes, however, the actual permeabilization of live bacterial cells and subsequen...

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Detalles Bibliográficos
Autores principales: Hein-Kristensen, Line, Knapp, Kolja M, Franzyk, Henrik, Gram, Lone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224213/
https://www.ncbi.nlm.nih.gov/pubmed/21693068
http://dx.doi.org/10.1186/1471-2180-11-144