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Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity

BACKGROUND: Epidermal growth factor receptor (EGFR) signaling plays an important role in the regulation of cell proliferation, survival, metastasis, and invasion in various tumors. Earlier studies showed that the EGFR is frequently overexpressed in non-small-cell lung cancer (NSCLC) and EGFR mutatio...

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Detalles Bibliográficos
Autores principales:	Naruo, Yoshimi, Nagashima, Takeshi, Ushikoshi-Nakayama, Ryoko, Saeki, Yuko, Nakakuki, Takashi, Naka, Takashi, Tanaka, Hiroshi, Tsai, Shih-Feng, Okada-Hatakeyama, Mariko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224393/ https://www.ncbi.nlm.nih.gov/pubmed/21333004 http://dx.doi.org/10.1186/1752-0509-5-29

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