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Genetic variation in the tau protein phosphatase-2A pathway is not associated with Alzheimer's disease risk

BACKGROUND: Tau abnormal hyperphosphorylation and the formation of neurofibrillary tangles in AD brain is the result of upregulation of tau kinases and downregulation of tau phosphatases. METHODS: In a group of 729 Spanish late-onset Alzheimer's disease (AD) patients and 670 healthy controls, w...

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Detalles Bibliográficos
Autores principales:	Vázquez-Higuera, José L, Mateo, Ignacio, Sánchez-Juan, Pascual, Rodríguez-Rodríguez, Eloy, Pozueta, Ana, Calero, Miguel, Dobato, José L, Frank-García, Ana, Valdivieso, Fernando, Berciano, José, Bullido, Maria J, Combarros, Onofre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224542/ https://www.ncbi.nlm.nih.gov/pubmed/21899770 http://dx.doi.org/10.1186/1756-0500-4-327

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