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SULFs in human neoplasia: implication as progression and prognosis factors

BACKGROUND: The sulfation pattern of heparan sulfate chains influences signaling events mediated by heparan sulfate proteoglycans located on cell surface. SULF1 and SULF2 are two endosulfatases able to cleave specific 6-O sulfate groups within the heparan chains. Their action can modulate signaling...

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Detalles Bibliográficos
Autores principales: Bret, Caroline, Moreaux, Jérôme, Schved, Jean-François, Hose, Dirk, Klein, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224561/
https://www.ncbi.nlm.nih.gov/pubmed/21599997
http://dx.doi.org/10.1186/1479-5876-9-72