Identification of specificity determining residues in peptide recognition domains using an information theoretic approach applied to large-scale binding maps

BACKGROUND: Peptide Recognition Domains (PRDs) are commonly found in signaling proteins. They mediate protein-protein interactions by recognizing and binding short motifs in their ligands. Although a great deal is known about PRDs and their interactions, prediction of PRD specificities remains large...

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Detalles Bibliográficos
Autores principales: Yip, Kevin Y, Utz, Lukas, Sitwell, Simon, Hu, Xihao, Sidhu, Sachdev S, Turk, Benjamin E, Gerstein, Mark, Kim, Philip M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224579/
https://www.ncbi.nlm.nih.gov/pubmed/21835011
http://dx.doi.org/10.1186/1741-7007-9-53

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