The role of mutational analysis of KIT and PDGFRA in gastrointestinal stromal tumors in a clinical setting

Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract. Most GIST harbor a mutation affecting either the KIT or PDGFRA genes, whereas a small subgroup of tumors is wild type for mutations. Mutation of tyrosine kinase receptors is a mechanism of dr...

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Detalles Bibliográficos
Autores principales: Maleddu, Alessandra, Pantaleo, Maria A, Nannini, Margherita, Biasco, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224648/
https://www.ncbi.nlm.nih.gov/pubmed/21605429
http://dx.doi.org/10.1186/1479-5876-9-75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224648/
https://www.ncbi.nlm.nih.gov/pubmed/21605429
http://dx.doi.org/10.1186/1479-5876-9-75

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