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Sequence variation of PfEMP1-DBLα in association with rosette formation in Plasmodium falciparum isolates causing severe and uncomplicated malaria

BACKGROUND: Rosetting and cytoadherence of Plasmodium falciparum-infected red blood cells have been associated with severity of malaria. ICAM-1 and CD36 are the main host cell receptors, while PfEMP1-DBLα is a major parasite ligand, which can contribute to rosette formation. This study is aimed at d...

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Detalles Bibliográficos
Autores principales:	Horata, Natharinee, Kalambaheti, Thareerat, Craig, Alister, Khusmith, Srisin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224928/ https://www.ncbi.nlm.nih.gov/pubmed/19650937 http://dx.doi.org/10.1186/1475-2875-8-184

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