Cargando…

Multidrug-resistant Intestinal Staphylococcus aureus among Self-medicated Healthy Adults in Amassoma, South-South, Nigeria

Multiple antibiotic resistant Staphylococcus aureus is one of the common causes of severe nosocomial infections, and the gastrointestinal tract is an important source of its transmission. This study assessed the previous usage of antibiotics by healthy adults (university students and villagers) in A...

Descripción completa

Detalles Bibliográficos
Autores principales: Onanuga, Adebola, Temedie, Tarilate C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Centre for Diarrhoeal Disease Research, Bangladesh 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225106/
https://www.ncbi.nlm.nih.gov/pubmed/22106750
_version_ 1782217477543952384
author Onanuga, Adebola
Temedie, Tarilate C.
author_facet Onanuga, Adebola
Temedie, Tarilate C.
author_sort Onanuga, Adebola
collection PubMed
description Multiple antibiotic resistant Staphylococcus aureus is one of the common causes of severe nosocomial infections, and the gastrointestinal tract is an important source of its transmission. This study assessed the previous usage of antibiotics by healthy adults (university students and villagers) in Amassoma, Nigeria, and investigated the antimicrobial resistance patterns of their intestinal S. aureus isolates. A questionnaire was used for evaluating the previous usage of antibiotics by the volunteers. Stool samples were collected and cultured, and S. aureus isolates were confirmed using standard microbiological protocols. Their antimicrobial resistance patterns were determined using disc-diffusion and agar dilution techniques. In total, 54 (45.0%) volunteers used antibiotics on self-medications, and the practice was significantly higher (p=0.01) among the villagers than among the students. The level of judicious use of prescribed antibiotics was significantly higher (p=0.003) among the students than among the villagers. Thirty-eight (31.7%) healthy adults were colonized with intestinal S. aureus. The percentages of resistance of the isolates to some antibiotics were as follows: ampicillin–68.4%, doxycycline–60.5%, cefoxitin–34.2%, vancomycin–36.8%, erythromycin–34.2%, and gentamicin–5.3%. Twenty-five (65.8%) of the isolates were multidrug-resistant. The need for sound education on the appropriate use of antibiotics and the importance of proper personal hygiene as means of controlling the spread of bacterial antibiotic resistance are highlighted. Thus, effective strategies in these areas are strongly recommended.
format Online
Article
Text
id pubmed-3225106
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher International Centre for Diarrhoeal Disease Research, Bangladesh
record_format MEDLINE/PubMed
spelling pubmed-32251062011-11-29 Multidrug-resistant Intestinal Staphylococcus aureus among Self-medicated Healthy Adults in Amassoma, South-South, Nigeria Onanuga, Adebola Temedie, Tarilate C. J Health Popul Nutr Original Papers Multiple antibiotic resistant Staphylococcus aureus is one of the common causes of severe nosocomial infections, and the gastrointestinal tract is an important source of its transmission. This study assessed the previous usage of antibiotics by healthy adults (university students and villagers) in Amassoma, Nigeria, and investigated the antimicrobial resistance patterns of their intestinal S. aureus isolates. A questionnaire was used for evaluating the previous usage of antibiotics by the volunteers. Stool samples were collected and cultured, and S. aureus isolates were confirmed using standard microbiological protocols. Their antimicrobial resistance patterns were determined using disc-diffusion and agar dilution techniques. In total, 54 (45.0%) volunteers used antibiotics on self-medications, and the practice was significantly higher (p=0.01) among the villagers than among the students. The level of judicious use of prescribed antibiotics was significantly higher (p=0.003) among the students than among the villagers. Thirty-eight (31.7%) healthy adults were colonized with intestinal S. aureus. The percentages of resistance of the isolates to some antibiotics were as follows: ampicillin–68.4%, doxycycline–60.5%, cefoxitin–34.2%, vancomycin–36.8%, erythromycin–34.2%, and gentamicin–5.3%. Twenty-five (65.8%) of the isolates were multidrug-resistant. The need for sound education on the appropriate use of antibiotics and the importance of proper personal hygiene as means of controlling the spread of bacterial antibiotic resistance are highlighted. Thus, effective strategies in these areas are strongly recommended. International Centre for Diarrhoeal Disease Research, Bangladesh 2011-10 /pmc/articles/PMC3225106/ /pubmed/22106750 Text en © INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH, BANGLADESH http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Papers
Onanuga, Adebola
Temedie, Tarilate C.
Multidrug-resistant Intestinal Staphylococcus aureus among Self-medicated Healthy Adults in Amassoma, South-South, Nigeria
title Multidrug-resistant Intestinal Staphylococcus aureus among Self-medicated Healthy Adults in Amassoma, South-South, Nigeria
title_full Multidrug-resistant Intestinal Staphylococcus aureus among Self-medicated Healthy Adults in Amassoma, South-South, Nigeria
title_fullStr Multidrug-resistant Intestinal Staphylococcus aureus among Self-medicated Healthy Adults in Amassoma, South-South, Nigeria
title_full_unstemmed Multidrug-resistant Intestinal Staphylococcus aureus among Self-medicated Healthy Adults in Amassoma, South-South, Nigeria
title_short Multidrug-resistant Intestinal Staphylococcus aureus among Self-medicated Healthy Adults in Amassoma, South-South, Nigeria
title_sort multidrug-resistant intestinal staphylococcus aureus among self-medicated healthy adults in amassoma, south-south, nigeria
topic Original Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225106/
https://www.ncbi.nlm.nih.gov/pubmed/22106750
work_keys_str_mv AT onanugaadebola multidrugresistantintestinalstaphylococcusaureusamongselfmedicatedhealthyadultsinamassomasouthsouthnigeria
AT temedietarilatec multidrugresistantintestinalstaphylococcusaureusamongselfmedicatedhealthyadultsinamassomasouthsouthnigeria