Generation and Characterization of Rat and Mouse Monoclonal Antibodies Specific for MeCP2 and Their Use in X-Inactivation Studies

Methyl CpG binding protein 2 (MeCP2) binds DNA, and has a preference for methylated CpGs and, hence, in cells, it accumulates in heterochromatin. Even though it is expressed ubiquitously MeCP2 is particularly important during neuronal maturation. This is underscored by the fact that in Rett syndrome...

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Detalles Bibliográficos
Autores principales: Jost, K. Laurence, Rottach, Andrea, Milden, Manuela, Bertulat, Bianca, Becker, Annette, Wolf, Patricia, Sandoval, Juan, Petazzi, Paolo, Huertas, Dori, Esteller, Manel, Kremmer, Elisabeth, Leonhardt, Heinrich, Cardoso, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225355/
https://www.ncbi.nlm.nih.gov/pubmed/22140431
http://dx.doi.org/10.1371/journal.pone.0026499

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