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Dual Function of Histone H3 Lysine 36 Methyltransferase ASH1 in Regulation of Hox Gene Expression

Hox genes play important roles in haematopoietic development in mammals. ASH1 is a member of the trithorax group (trxG) that is required for proper expression of Hox genes and is preferentially expressed in haematopoietic stem cells. We have recently reported that ASH1 methylates histone H3 at lysin...

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Detalles Bibliográficos
Autores principales: Tanaka, Yujiro, Kawahashi, Koji, Katagiri, Zen-Ichiro, Nakayama, Yasuhiro, Mahajan, Milind, Kioussis, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225378/
https://www.ncbi.nlm.nih.gov/pubmed/22140534
http://dx.doi.org/10.1371/journal.pone.0028171

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