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Epigenetic Modulation of miR-122 Facilitates Human Embryonic Stem Cell Self-Renewal and Hepatocellular Carcinoma Proliferation
The self-renewal capacity ascribed to hESCs is paralleled in cancer cell proliferation, suggesting that a common network of genes may facilitate the promotion of these traits. However, the molecular mechanisms that are involved in regulating the silencing of these genes as stem cells differentiate i...
Autores principales: | Jung, Christine J., Iyengar, Sushma, Blahnik, Kimberly R., Ajuha, Tijess P., Jiang, Joy X., Farnham, Peggy J., Zern, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225380/ https://www.ncbi.nlm.nih.gov/pubmed/22140464 http://dx.doi.org/10.1371/journal.pone.0027740 |
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