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Surgically induced necrotizing scleritis after primary pterygium surgery with conjunctival autograft

BACKGROUND: Although pterygium excision with conjunctival autograft is a widely performed surgical procedure, surgically induced necrotizing scleritis (SINS) following such surgery is extremely rare. METHODS: A 68-year-old man underwent nasal pterygium excision with conjunctival autograft uneventful...

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Autores principales: Yamazoe, Katsuya, Shimazaki-Den, Seika, Otaka, Isao, Hotta, Kazuki, Shimazaki, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225457/
https://www.ncbi.nlm.nih.gov/pubmed/22140306
http://dx.doi.org/10.2147/OPTH.S24885
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author Yamazoe, Katsuya
Shimazaki-Den, Seika
Otaka, Isao
Hotta, Kazuki
Shimazaki, Jun
author_facet Yamazoe, Katsuya
Shimazaki-Den, Seika
Otaka, Isao
Hotta, Kazuki
Shimazaki, Jun
author_sort Yamazoe, Katsuya
collection PubMed
description BACKGROUND: Although pterygium excision with conjunctival autograft is a widely performed surgical procedure, surgically induced necrotizing scleritis (SINS) following such surgery is extremely rare. METHODS: A 68-year-old man underwent nasal pterygium excision with conjunctival autograft uneventfully. On postoperative day 17, the conjunctival graft was avascular, with epithelial defect. Although topical steroid and antibacterial treatments were continued, the graft and sclera melted, with the ischemic sclera showing gradual thinning. The thinning area spread to the adjoining cornea, and active inflammation with epithelial defect was observed adjacent to the site of thinning. RESULTS: Systemic and microbiological examination was noncontributory. The patient was suspected of having SINS, and administration of oral prednisolone was started. Although the necrotic area was reduced temporarily, medication was discontinued due to nausea, and the area of thinning increased. Conjunctival flap surgery was later performed, and the graft was well accepted. CONCLUSIONS: SINS must be considered in the differential diagnosis of patients with scleritis following pterygium surgery, especially if radiation or mitomycin C has not been used.
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spelling pubmed-32254572011-12-02 Surgically induced necrotizing scleritis after primary pterygium surgery with conjunctival autograft Yamazoe, Katsuya Shimazaki-Den, Seika Otaka, Isao Hotta, Kazuki Shimazaki, Jun Clin Ophthalmol Case Report BACKGROUND: Although pterygium excision with conjunctival autograft is a widely performed surgical procedure, surgically induced necrotizing scleritis (SINS) following such surgery is extremely rare. METHODS: A 68-year-old man underwent nasal pterygium excision with conjunctival autograft uneventfully. On postoperative day 17, the conjunctival graft was avascular, with epithelial defect. Although topical steroid and antibacterial treatments were continued, the graft and sclera melted, with the ischemic sclera showing gradual thinning. The thinning area spread to the adjoining cornea, and active inflammation with epithelial defect was observed adjacent to the site of thinning. RESULTS: Systemic and microbiological examination was noncontributory. The patient was suspected of having SINS, and administration of oral prednisolone was started. Although the necrotic area was reduced temporarily, medication was discontinued due to nausea, and the area of thinning increased. Conjunctival flap surgery was later performed, and the graft was well accepted. CONCLUSIONS: SINS must be considered in the differential diagnosis of patients with scleritis following pterygium surgery, especially if radiation or mitomycin C has not been used. Dove Medical Press 2011 2011-11-10 /pmc/articles/PMC3225457/ /pubmed/22140306 http://dx.doi.org/10.2147/OPTH.S24885 Text en © 2011 Yamazoe et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Case Report
Yamazoe, Katsuya
Shimazaki-Den, Seika
Otaka, Isao
Hotta, Kazuki
Shimazaki, Jun
Surgically induced necrotizing scleritis after primary pterygium surgery with conjunctival autograft
title Surgically induced necrotizing scleritis after primary pterygium surgery with conjunctival autograft
title_full Surgically induced necrotizing scleritis after primary pterygium surgery with conjunctival autograft
title_fullStr Surgically induced necrotizing scleritis after primary pterygium surgery with conjunctival autograft
title_full_unstemmed Surgically induced necrotizing scleritis after primary pterygium surgery with conjunctival autograft
title_short Surgically induced necrotizing scleritis after primary pterygium surgery with conjunctival autograft
title_sort surgically induced necrotizing scleritis after primary pterygium surgery with conjunctival autograft
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225457/
https://www.ncbi.nlm.nih.gov/pubmed/22140306
http://dx.doi.org/10.2147/OPTH.S24885
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