Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction

Quantitative trait locus mapping of chemical/inflammatory pain in the mouse identified the Avpr1a gene, encoding the vasopressin-1A receptor (V1AR), as responsible for strain-dependent pain sensitivity to formalin and capsaicin. A genetic association study in humans revealed the influence of a singl...

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Detalles Bibliográficos
Autores principales: Mogil, Jeffrey S., Sorge, Robert E., LaCroix-Fralish, Michael L., Smith, Shad B., Fortin, Anny, Sotocinal, Susana G., Ritchie, Jennifer, Austin, Jean-Sebastien, Schorscher-Petcu, Ara, Melmed, Kara, Czerminski, Jan, Bittong, Rosalie A., Mokris, J. Brad, Neubert, John K., Campbell, Claudia M., Edwards, Robert R., Campbell, James N., Crawley, Jacqueline N., Lariviere, William R., Wallace, Margaret R., Sternberg, Wendy F., Balaban, Carey D., Belfer, Inna, Fillingim, Roger B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225498/
https://www.ncbi.nlm.nih.gov/pubmed/22019732
http://dx.doi.org/10.1038/nn.2941

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