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Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp

Two new metabolites, including a lindenane-type sesquiterpenoid, menelloide C (1), and a germacrane-type sesquiterpenoid, menelloide D (2), were isolated from a Formosan gorgonian coral identified as Menella sp. The structures of 1 and 2 were established by spectroscopic methods and 2 displayed a we...

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Detalles Bibliográficos
Autores principales: Kao, Shih-Yao, Su, Jui-Hsin, Hwang, Tsong-Long, Sheu, Jyh-Horng, Wen, Zhi-Hong, Wu, Yang-Chang, Sung, Ping-Jyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225933/
https://www.ncbi.nlm.nih.gov/pubmed/22131956
http://dx.doi.org/10.3390/md9091534
Descripción
Sumario:Two new metabolites, including a lindenane-type sesquiterpenoid, menelloide C (1), and a germacrane-type sesquiterpenoid, menelloide D (2), were isolated from a Formosan gorgonian coral identified as Menella sp. The structures of 1 and 2 were established by spectroscopic methods and 2 displayed a weak inhibitory effect on the release of elastase by human neutrophils.