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Selectivity to amyloid-β precursor protein cleavage provides hope against Alzheimer's

Toward development of a safe and effective treatment for Alzheimer's disease, Elan Pharmaceuticals reported a novel γ-secretase inhibitor that specifically targets the cleavage of amyloid-β precursor protein, opening the way to design of substrate-specific γ-secretase inhibitors that would redu...

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Detalles Bibliográficos
Autores principales:	Tomita, Taisuke, Wong, Philip C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226269/ https://www.ncbi.nlm.nih.gov/pubmed/21418547 http://dx.doi.org/10.1186/alzrt66

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