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The Stability and Complexity of Antibody Responses to the Major Surface Antigen of Plasmodium falciparum Are Associated with Age in a Malaria Endemic Area
Individuals that are exposed to malaria eventually develop immunity to the disease with one possible mechanism being the gradual acquisition of antibodies to the range of parasite variant surface antigens in their local area. Major antibody targets include the large and highly polymorphic Plasmodium...
Autores principales: | Barry, Alyssa E., Trieu, Angela, Fowkes, Freya J. I, Pablo, Jozelyn, Kalantari-Dehaghi, Mina, Jasinskas, Algis, Tan, Xiaolin, Kayala, Matthew A., Tavul, Livingstone, Siba, Peter M., Day, Karen P., Baldi, Pierre, Felgner, Philip L., Doolan, Denise L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226400/ https://www.ncbi.nlm.nih.gov/pubmed/21825279 http://dx.doi.org/10.1074/mcp.M111.008326 |
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