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Malignant Hyperthermia and Idiopathic HyperCKemia
Malignant hyperthermia (MH) is a rare but life-threatening condition that is more frequently encountered and discussed within the anesthesia literature. Here we through a case specifically discuss the susceptibility of individuals and/or families with asymptomatic unexplained elevations of creatine...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226427/ https://www.ncbi.nlm.nih.gov/pubmed/22162697 http://dx.doi.org/10.1155/2011/194296 |
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author | Kasi, Pashtoon Murtaza |
author_facet | Kasi, Pashtoon Murtaza |
author_sort | Kasi, Pashtoon Murtaza |
collection | PubMed |
description | Malignant hyperthermia (MH) is a rare but life-threatening condition that is more frequently encountered and discussed within the anesthesia literature. Here we through a case specifically discuss the susceptibility of individuals and/or families with asymptomatic unexplained elevations of creatine kinase (CK), also frequently referred to as hyperCKemia or idiopathic hyperCKemia (IHCK) in recent reports. The clinical implications would be to underscore the importance of this as a susceptibility to developing MH and highlight the importance of genetic susceptibility testing in such cases. Anesthesiologists and critical care intensivists as well as primary care physicians should keep this in mind when seeing patients with asymptomatic hyperCKemia and potentially inform them about the possibility of developing MH if exposed to triggering agents. Genetic susceptibility testing should be considered if available and family members should also receive nontriggering agents when undergoing anesthesia and wear Medic Alert tags. |
format | Online Article Text |
id | pubmed-3226427 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-32264272011-12-08 Malignant Hyperthermia and Idiopathic HyperCKemia Kasi, Pashtoon Murtaza Case Rep Med Case Report Malignant hyperthermia (MH) is a rare but life-threatening condition that is more frequently encountered and discussed within the anesthesia literature. Here we through a case specifically discuss the susceptibility of individuals and/or families with asymptomatic unexplained elevations of creatine kinase (CK), also frequently referred to as hyperCKemia or idiopathic hyperCKemia (IHCK) in recent reports. The clinical implications would be to underscore the importance of this as a susceptibility to developing MH and highlight the importance of genetic susceptibility testing in such cases. Anesthesiologists and critical care intensivists as well as primary care physicians should keep this in mind when seeing patients with asymptomatic hyperCKemia and potentially inform them about the possibility of developing MH if exposed to triggering agents. Genetic susceptibility testing should be considered if available and family members should also receive nontriggering agents when undergoing anesthesia and wear Medic Alert tags. Hindawi Publishing Corporation 2011 2011-11-23 /pmc/articles/PMC3226427/ /pubmed/22162697 http://dx.doi.org/10.1155/2011/194296 Text en Copyright © 2011 Pashtoon Murtaza Kasi. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kasi, Pashtoon Murtaza Malignant Hyperthermia and Idiopathic HyperCKemia |
title | Malignant Hyperthermia and Idiopathic HyperCKemia |
title_full | Malignant Hyperthermia and Idiopathic HyperCKemia |
title_fullStr | Malignant Hyperthermia and Idiopathic HyperCKemia |
title_full_unstemmed | Malignant Hyperthermia and Idiopathic HyperCKemia |
title_short | Malignant Hyperthermia and Idiopathic HyperCKemia |
title_sort | malignant hyperthermia and idiopathic hyperckemia |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226427/ https://www.ncbi.nlm.nih.gov/pubmed/22162697 http://dx.doi.org/10.1155/2011/194296 |
work_keys_str_mv | AT kasipashtoonmurtaza malignanthyperthermiaandidiopathichyperckemia |