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Prevalence of cognitive impairment in individuals aged over 65 in an urban area: DERIVA study

BACKGROUND: Few data are available on the prevalence of cognitive impairment (CI) in Spain, and the existing information shows important variations depending on the geographical setting and the methodology employed. The aim of this study was to determine the prevalence of CI in individuals aged over...

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Autores principales: Rodríguez-Sánchez, Emiliano, Mora-Simón, Sara, Patino-Alonso, María C, García-García, Ricardo, Escribano-Hernández, Alfonso, García-Ortiz, Luis, Perea- Bartolomé, Ma Victoria, Gómez-Marcos, Manuel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226440/
https://www.ncbi.nlm.nih.gov/pubmed/22093337
http://dx.doi.org/10.1186/1471-2377-11-147
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author Rodríguez-Sánchez, Emiliano
Mora-Simón, Sara
Patino-Alonso, María C
García-García, Ricardo
Escribano-Hernández, Alfonso
García-Ortiz, Luis
Perea- Bartolomé, Ma Victoria
Gómez-Marcos, Manuel A
author_facet Rodríguez-Sánchez, Emiliano
Mora-Simón, Sara
Patino-Alonso, María C
García-García, Ricardo
Escribano-Hernández, Alfonso
García-Ortiz, Luis
Perea- Bartolomé, Ma Victoria
Gómez-Marcos, Manuel A
author_sort Rodríguez-Sánchez, Emiliano
collection PubMed
description BACKGROUND: Few data are available on the prevalence of cognitive impairment (CI) in Spain, and the existing information shows important variations depending on the geographical setting and the methodology employed. The aim of this study was to determine the prevalence of CI in individuals aged over 65 in an urban area, and to analyze its associated risk factors. METHODS: Design: A descriptive, cross-sectional, home questionnaire-based study; Setting: Populational, urban setting. Participants: The reference population comprised over-65s living in the city of Salamanca (Spain) in 2009. Randomized sampling stratified according to health district was carried out, and a total of 480 people were selected. In all, 327 patients were interviewed (68.10%), with a mean age of 76.35 years (SD: 7.33). Women accounted for 64.5% of the total. Measurements: A home health questionnaire was used to obtain the following data: age, sex, educational level, family structure, morbidity and functionality. All participants completed a neuropsychological test battery. The prevalence data were compared with those of the European population, with direct adjustment for age and sex. Diagnoses were divided into three general categories: normal cognitive function, cognitive impairment - no dementia (CIND), and dementia. RESULTS: The prevalence of CI among these over-65s was 19% (14.7% CIND and 4.3% dementia). The age-and sex-adjusted global prevalence of CI was 14.9%. CI increased with age (p < 0.001) and decreased with increasing educational level (p < 0.001). Significant risk factors were found with the multivariate analyses: age (OR = 1.08, 95%CI: 1.03-1.12), anxiety-depression (OR = 3.47, 95%CI: 1.61-7.51) and diabetes (OR = 2.07, 95%CI: 1.02-4.18). In turn, years of education was found to be a protective factor (OR = 0.79, 95%CI: 0.70-0.90). Although CI was more frequent among women and in people living without a partner, these characteristics were not significantly associated with CI risk. CONCLUSIONS: The observed raw prevalence of CI was 19% (14.9% after adjusting for age and sex). Older age and the presence of diabetes and anxiety-depression increased the risk of CI, while higher educational level reduced the risk.
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spelling pubmed-32264402011-11-30 Prevalence of cognitive impairment in individuals aged over 65 in an urban area: DERIVA study Rodríguez-Sánchez, Emiliano Mora-Simón, Sara Patino-Alonso, María C García-García, Ricardo Escribano-Hernández, Alfonso García-Ortiz, Luis Perea- Bartolomé, Ma Victoria Gómez-Marcos, Manuel A BMC Neurol Research Article BACKGROUND: Few data are available on the prevalence of cognitive impairment (CI) in Spain, and the existing information shows important variations depending on the geographical setting and the methodology employed. The aim of this study was to determine the prevalence of CI in individuals aged over 65 in an urban area, and to analyze its associated risk factors. METHODS: Design: A descriptive, cross-sectional, home questionnaire-based study; Setting: Populational, urban setting. Participants: The reference population comprised over-65s living in the city of Salamanca (Spain) in 2009. Randomized sampling stratified according to health district was carried out, and a total of 480 people were selected. In all, 327 patients were interviewed (68.10%), with a mean age of 76.35 years (SD: 7.33). Women accounted for 64.5% of the total. Measurements: A home health questionnaire was used to obtain the following data: age, sex, educational level, family structure, morbidity and functionality. All participants completed a neuropsychological test battery. The prevalence data were compared with those of the European population, with direct adjustment for age and sex. Diagnoses were divided into three general categories: normal cognitive function, cognitive impairment - no dementia (CIND), and dementia. RESULTS: The prevalence of CI among these over-65s was 19% (14.7% CIND and 4.3% dementia). The age-and sex-adjusted global prevalence of CI was 14.9%. CI increased with age (p < 0.001) and decreased with increasing educational level (p < 0.001). Significant risk factors were found with the multivariate analyses: age (OR = 1.08, 95%CI: 1.03-1.12), anxiety-depression (OR = 3.47, 95%CI: 1.61-7.51) and diabetes (OR = 2.07, 95%CI: 1.02-4.18). In turn, years of education was found to be a protective factor (OR = 0.79, 95%CI: 0.70-0.90). Although CI was more frequent among women and in people living without a partner, these characteristics were not significantly associated with CI risk. CONCLUSIONS: The observed raw prevalence of CI was 19% (14.9% after adjusting for age and sex). Older age and the presence of diabetes and anxiety-depression increased the risk of CI, while higher educational level reduced the risk. BioMed Central 2011-11-17 /pmc/articles/PMC3226440/ /pubmed/22093337 http://dx.doi.org/10.1186/1471-2377-11-147 Text en Copyright ©2011 Rodríguez-Sánchez et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Rodríguez-Sánchez, Emiliano
Mora-Simón, Sara
Patino-Alonso, María C
García-García, Ricardo
Escribano-Hernández, Alfonso
García-Ortiz, Luis
Perea- Bartolomé, Ma Victoria
Gómez-Marcos, Manuel A
Prevalence of cognitive impairment in individuals aged over 65 in an urban area: DERIVA study
title Prevalence of cognitive impairment in individuals aged over 65 in an urban area: DERIVA study
title_full Prevalence of cognitive impairment in individuals aged over 65 in an urban area: DERIVA study
title_fullStr Prevalence of cognitive impairment in individuals aged over 65 in an urban area: DERIVA study
title_full_unstemmed Prevalence of cognitive impairment in individuals aged over 65 in an urban area: DERIVA study
title_short Prevalence of cognitive impairment in individuals aged over 65 in an urban area: DERIVA study
title_sort prevalence of cognitive impairment in individuals aged over 65 in an urban area: deriva study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226440/
https://www.ncbi.nlm.nih.gov/pubmed/22093337
http://dx.doi.org/10.1186/1471-2377-11-147
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