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Selective targeted delivery of the TNF-alpha receptor p75 and uteroglobin to the vasculature of inflamed tissues: a preliminary report
BACKGROUND: Ligand-targeted approaches have proven successful in improving the therapeutic index of a number of drugs. We hypothesized that the specific targeting of TNF-alpha antagonists to inflamed tissues could increase drug efficacy and reduce side effects. RESULTS: Using uteroglobin (UG), a pot...
Autores principales: | Ventura, Elisa, Balza, Enrica, Borsi, Laura, Tutolo, Giorgia, Carnemolla, Barbara, Castellani, Patrizia, Zardi, Luciano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226451/ https://www.ncbi.nlm.nih.gov/pubmed/22074550 http://dx.doi.org/10.1186/1472-6750-11-104 |
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