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Alteration of CFTR transmembrane span integration by disease-causing mutations

Many missense mutations in the cystic fibrosis transmembrane conductance regulator protein (CFTR) result in its misfolding, endoplasmic reticulum (ER) accumulation, and, thus, cystic fibrosis. A number of these mutations are located in the predicted CFTR transmembrane (TM) spans and have been projec...

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Detalles Bibliográficos
Autores principales:	Patrick, Anna E., Karamyshev, Andrey L., Millen, Linda, Thomas, Philip J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226467/ https://www.ncbi.nlm.nih.gov/pubmed/21998193 http://dx.doi.org/10.1091/mbc.E11-05-0396

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