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Development of an optimized backbone of FRET biosensors for kinases and GTPases

Biosensors based on the principle of Förster (or fluorescence) resonance energy transfer (FRET) have shed new light on the spatiotemporal dynamics of signaling molecules. Among them, intramolecular FRET biosensors have been increasingly used due to their high sensitivity and user-friendliness. Time-...

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Detalles Bibliográficos
Autores principales: Komatsu, Naoki, Aoki, Kazuhiro, Yamada, Masashi, Yukinaga, Hiroko, Fujita, Yoshihisa, Kamioka, Yuji, Matsuda, Michiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226481/
https://www.ncbi.nlm.nih.gov/pubmed/21976697
http://dx.doi.org/10.1091/mbc.E11-01-0072