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Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1

In human cells, the mRNA export factor NXF1 resides in the nucleoplasm and at nuclear pore complexes. Karyopherin β2 or transportin recognizes a proline–tyrosine nuclear localization signal (PY-NLS) in the N-terminal tail of NXF1 and imports it into the nucleus. Here biochemical and cellular studies...

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Detalles Bibliográficos
Autores principales:	Zhang, Zi Chao, Satterly, Neal, Fontoura, Beatriz M. A., Chook, Yuh Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226482/ https://www.ncbi.nlm.nih.gov/pubmed/21965294 http://dx.doi.org/10.1091/mbc.E11-03-0222

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