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Differential Combination of Cytokine and Interferon- γ +874 T/A Polymorphisms Determines Disease Severity in Pulmonary Tuberculosis

BACKGROUND: Mycobacterium tuberculosis infects nearly 1/3 of the world population and this reservoir forms the largest pool from which new cases arise. Among the cytokines, IFN-γ is a key determinant in protection against tuberculosis. Single nucleotide polymorphisms (SNPs) in IFN-γ gene (+874 T/A)...

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Detalles Bibliográficos
Autores principales:	Ansari, Ambreen, Hasan, Zahra, Dawood, Ghaffar, Hussain, Rabia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226558/ https://www.ncbi.nlm.nih.gov/pubmed/22140472 http://dx.doi.org/10.1371/journal.pone.0027848

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