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Stem Cell Antigen-1 (Sca-1) Regulates Mammary Tumor Development and Cell Migration
BACKGROUND: Stem cell antigen-1 (Sca-1 or Ly6A) is a glycosyl phostidylinositol (GPI)-anchored cell surface protein associated with both stem and progenitor activity, as well as tumor initiating-potential. However, at present the functional role for Sca-1 is poorly defined. METHODOLOGY/PRINCIPAL FIN...
Autores principales: | Batts, Torey D., Machado, Heather L., Zhang, Yiqun, Creighton, Chad J., Li, Yi, Rosen, Jeffrey M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226565/ https://www.ncbi.nlm.nih.gov/pubmed/22140470 http://dx.doi.org/10.1371/journal.pone.0027841 |
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