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Raloxifene and Desmethylarzoxifene Block Estrogen-Induced Malignant Transformation of Human Breast Epithelial Cells
There is association between exposure to estrogens and the development and progression of hormone-dependent gynecological cancers. Chemical carcinogenesis by catechol estrogens derived from oxidative metabolism is thought to contribute to breast cancer, yet exact mechanisms remain elusive. Malignant...
Autores principales: | Kastrati, Irida, Edirisinghe, Praneeth D., Hemachandra, L-P-Madhubani P., Chandrasena, Esala R., Choi, Jaewoo, Wang, Yue-Ting, Bolton, Judy L., Thatcher, Gregory R. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226622/ https://www.ncbi.nlm.nih.gov/pubmed/22140478 http://dx.doi.org/10.1371/journal.pone.0027876 |
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