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The Transient Receptor Potential Ion Channel TRPV6 Is Expressed at Low Levels in Osteoblasts and Has Little Role in Osteoblast Calcium Uptake

BACKGROUND: TRPV6 ion channels are key mediators of regulated transepithelial absorption of Ca(2+) within the small intestine. Trpv6 (-/-) mice were reported to have lower bone density than wild-type littermates and significant disturbances in calcium homeostasis that suggested a role for TRPV6 in o...

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Detalles Bibliográficos
Autores principales: Little, Robert, Muimo, Richmond, Robson, Louise, Harris, Kate, Grabowski, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226639/
https://www.ncbi.nlm.nih.gov/pubmed/22163264
http://dx.doi.org/10.1371/journal.pone.0028166

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