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Improved sensitivity of an interferon-gamma release assay (T-SPOT.TB™) in combination with tuberculin skin test for the diagnosis of latent tuberculosis in the presence of HIV co-Infection

BACKGROUND: Interferon-gamma release assays (IGRA) are more specific than the tuberculin skin test (TST) for the diagnosis of Mycobacterium tuberculosis infection. Data on sensitivity are controversial in HIV infection. METHODS: IGRA (T-SPOT.TB) was performed using lymphocytes stored within 6 months...

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Detalles Bibliográficos
Autores principales: Elzi, Luigia, Steffen, Ingrid, Furrer, Hansjakob, Fehr, Jan, Cavassini, Matthias, Hirschel, Bernard, Hoffmann, Matthias, Bernasconi, Enos, Bassetti, Stefano, Battegay, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226666/
https://www.ncbi.nlm.nih.gov/pubmed/22085801
http://dx.doi.org/10.1186/1471-2334-11-319