Cargando…
A Knockout Mutation of a Constitutive GPCR in Tetrahymena Decreases Both G-Protein Activity and Chemoattraction
Although G-protein coupled receptors (GPCRs) are a common element in many chemosensory transduction pathways in eukaryotic cells, no GPCR or regulated G-protein activity has yet been shown in any ciliate. To study the possible role for a GPCR in the chemoresponses of the ciliate Tetrahymena, we have...
Autores principales: | Lampert, Thomas J., Coleman, Kevin D., Hennessey, Todd M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226668/ https://www.ncbi.nlm.nih.gov/pubmed/22140501 http://dx.doi.org/10.1371/journal.pone.0028022 |
Ejemplares similares
-
Behavioral Effects of a Chemorepellent Receptor Knockout Mutation in Tetrahymena thermophila
por: Zou, Dianxiong, et al.
Publicado: (2017) -
Responses of the ciliates Tetrahymena and Paramecium to external ATP and GTP
por: Hennessey, Todd M.
Publicado: (2005) -
A systems approach to investigate GPCR-mediated Ras signaling network in chemoattractant sensing
por: Xu, Xuehua, et al.
Publicado: (2022) -
Mutation accumulation in Tetrahymena
por: Brito, Patrícia H, et al.
Publicado: (2010) -
GPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulation
por: Drube, J., et al.
Publicado: (2022)