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The Role of Palmitoylation in Signalling, Cellular Trafficking and Plasma Membrane Localization of Protease-Activated Receptor-2

Protease-activated receptor-2 (PAR2) is a G protein coupled receptor (GPCR) activated by proteolytic cleavage of its amino terminal domain by trypsin-like serine proteases. This irreversible activation mechanism leads to rapid receptor desensitization by internalisation and degradation. We have expl...

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Detalles Bibliográficos
Autores principales:	Adams, Mark N., Christensen, Melinda E., He, Yaowu, Waterhouse, Nigel J., Hooper, John D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226677/ https://www.ncbi.nlm.nih.gov/pubmed/22140500 http://dx.doi.org/10.1371/journal.pone.0028018

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