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Small interfering RNA targeting mcl-1 enhances proteasome inhibitor-induced apoptosis in various solid malignant tumors

BACKGROUND: Targeting the ubiquitin-proteasome pathway is a promising approach for anticancer strategies. Recently, we found Bik accumulation in cancer cell lines after they were treated with bortezomib. However, recent evidence indicates that proteasome inhibitors may also induce the accumulation o...

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Detalles Bibliográficos
Autores principales:	Zhou, Wei, Hu, Jingzi, Tang, Haimei, Wang, Da, Huang, Xuefeng, He, Chao, Zhu, Hongbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226681/ https://www.ncbi.nlm.nih.gov/pubmed/22078414 http://dx.doi.org/10.1186/1471-2407-11-485

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