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A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
Natural products that elicit discomfort or pain represent invaluable tools for probing molecular mechanisms underlying pain sensation(1). Plant-derived irritants have predominated in this regard, but animal venoms have also evolved to avert predators by targeting neurons and receptors whose activati...
Autores principales: | Bohlen, Christopher J., Chesler, Alexander T., Sharif-Naeini, Reza, Medzihradszky, Katalin F., Zhou, Sharleen, King, David, Sánchez, Elda E., Burlingame, Alma L., Basbaum, Allan I., Julius, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226747/ https://www.ncbi.nlm.nih.gov/pubmed/22094702 http://dx.doi.org/10.1038/nature10607 |
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