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Understanding the Mechanism of Insulin and Insulin-Like Growth Factor (IGF) Receptor Activation by IGF-II

BACKGROUND: Insulin-like growth factor-II (IGF-II) promotes cell proliferation and survival and plays an important role in normal fetal development and placental function. IGF-II binds both the insulin-like growth factor receptor (IGF-1R) and insulin receptor isoform A (IR-A) with high affinity. Int...

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Detalles Bibliográficos
Autores principales:	Alvino, Clair L., Ong, Shee Chee, McNeil, Kerrie A., Delaine, Carlie, Booker, Grant W., Wallace, John C., Forbes, Briony E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227035/ https://www.ncbi.nlm.nih.gov/pubmed/22140443 http://dx.doi.org/10.1371/journal.pone.0027488

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