Diabetes mellitus: The long way of standardization of HbA(1c) to the level of highest metrological order

Glycated haemoglobin (HbA(1c)) measurements are used in clinical studies and for the management of diabetic patients. Various efforts were made to standardize the HbA(1c) measurements with consensus standards and standards based on a reference measurement procedure with external calibration. Accordi...

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Detalles Bibliográficos
Autores principales: Kaiser, Patricia, Reinauer, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: German Medical Science GMS Publishing House 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227124/
https://www.ncbi.nlm.nih.gov/pubmed/22135621
http://dx.doi.org/10.3205/000151
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author Kaiser, Patricia
Reinauer, Hans
author_facet Kaiser, Patricia
Reinauer, Hans
author_sort Kaiser, Patricia
collection PubMed
description Glycated haemoglobin (HbA(1c)) measurements are used in clinical studies and for the management of diabetic patients. Various efforts were made to standardize the HbA(1c) measurements with consensus standards and standards based on a reference measurement procedure with external calibration. According to ISO 17511 a standard should meet highest accuracy possible, have a defined uncertainty of measurement and the calibration should be traceable to SI units. For HbA(1c) this has been realized using a LC-ID-MS procedure based on the existing reference measurement procedure.
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spelling pubmed-32271242011-12-01 Diabetes mellitus: The long way of standardization of HbA(1c) to the level of highest metrological order Kaiser, Patricia Reinauer, Hans Ger Med Sci Article Glycated haemoglobin (HbA(1c)) measurements are used in clinical studies and for the management of diabetic patients. Various efforts were made to standardize the HbA(1c) measurements with consensus standards and standards based on a reference measurement procedure with external calibration. According to ISO 17511 a standard should meet highest accuracy possible, have a defined uncertainty of measurement and the calibration should be traceable to SI units. For HbA(1c) this has been realized using a LC-ID-MS procedure based on the existing reference measurement procedure. German Medical Science GMS Publishing House 2011-11-09 /pmc/articles/PMC3227124/ /pubmed/22135621 http://dx.doi.org/10.3205/000151 Text en Copyright © 2011 Kaiser et al. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free to copy, distribute and transmit the work, provided the original author and source are credited.
spellingShingle Article
Kaiser, Patricia
Reinauer, Hans
Diabetes mellitus: The long way of standardization of HbA(1c) to the level of highest metrological order
title Diabetes mellitus: The long way of standardization of HbA(1c) to the level of highest metrological order
title_full Diabetes mellitus: The long way of standardization of HbA(1c) to the level of highest metrological order
title_fullStr Diabetes mellitus: The long way of standardization of HbA(1c) to the level of highest metrological order
title_full_unstemmed Diabetes mellitus: The long way of standardization of HbA(1c) to the level of highest metrological order
title_short Diabetes mellitus: The long way of standardization of HbA(1c) to the level of highest metrological order
title_sort diabetes mellitus: the long way of standardization of hba(1c) to the level of highest metrological order
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227124/
https://www.ncbi.nlm.nih.gov/pubmed/22135621
http://dx.doi.org/10.3205/000151
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