Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles

The ability of an oocyte to successfully mature is highly dependent on intrafollicular conditions, including the size and structure of the follicle. Here we present a mathematical model of oxygen transport in the antral follicle. We relate mean oxygen concentration in follicular fluid of bovine foll...

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Detalles Bibliográficos
Autores principales: Clark, A. R., Stokes, Y. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227233/
https://www.ncbi.nlm.nih.gov/pubmed/22162722
http://dx.doi.org/10.1155/2011/287186
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author Clark, A. R.
Stokes, Y. M.
author_facet Clark, A. R.
Stokes, Y. M.
author_sort Clark, A. R.
collection PubMed
description The ability of an oocyte to successfully mature is highly dependent on intrafollicular conditions, including the size and structure of the follicle. Here we present a mathematical model of oxygen transport in the antral follicle. We relate mean oxygen concentration in follicular fluid of bovine follicles to the concentration in the immediate vicinity of the cumulus-oocyte complex (COC). The model predicts that the oxygen levels within the antral follicle are dependent on the size and structure of the follicle and that the mean level of dissolved oxygen in follicular fluid does not necessarily correspond to that reaching the COC.
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spelling pubmed-32272332011-12-08 Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles Clark, A. R. Stokes, Y. M. Comput Math Methods Med Research Article The ability of an oocyte to successfully mature is highly dependent on intrafollicular conditions, including the size and structure of the follicle. Here we present a mathematical model of oxygen transport in the antral follicle. We relate mean oxygen concentration in follicular fluid of bovine follicles to the concentration in the immediate vicinity of the cumulus-oocyte complex (COC). The model predicts that the oxygen levels within the antral follicle are dependent on the size and structure of the follicle and that the mean level of dissolved oxygen in follicular fluid does not necessarily correspond to that reaching the COC. Hindawi Publishing Corporation 2011 2011-11-17 /pmc/articles/PMC3227233/ /pubmed/22162722 http://dx.doi.org/10.1155/2011/287186 Text en Copyright © 2011 A. R. Clark and Y. M. Stokes. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Clark, A. R.
Stokes, Y. M.
Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles
title Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles
title_full Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles
title_fullStr Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles
title_full_unstemmed Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles
title_short Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles
title_sort follicle structure influences the availability of oxygen to the oocyte in antral follicles
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227233/
https://www.ncbi.nlm.nih.gov/pubmed/22162722
http://dx.doi.org/10.1155/2011/287186
work_keys_str_mv AT clarkar folliclestructureinfluencestheavailabilityofoxygentotheoocyteinantralfollicles
AT stokesym folliclestructureinfluencestheavailabilityofoxygentotheoocyteinantralfollicles

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