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HLA Class II Defects in Burkitt Lymphoma: Bryostatin-1-Induced 17 kDa Protein Restores CD4+ T-Cell Recognition
While the defects in HLA class I-mediated Ag presentation by Burkitt lymphoma (BL) have been well documented, CD4+ T-cells are also poorly stimulated by HLA class II Ag presentation, and the reasons underlying this defect(s) have not yet been fully resolved. Here, we show that BL cells are deficient...
Autores principales: | Hossain, Azim, God, Jason M., Radwan, Faisal F. Y., Amria, Shereen, Zhao, Dan, Bethard, Jennifer R., Haque, Azizul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227386/ https://www.ncbi.nlm.nih.gov/pubmed/22162713 http://dx.doi.org/10.1155/2011/780839 |
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