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HLA Class II Defects in Burkitt Lymphoma: Bryostatin-1-Induced 17 kDa Protein Restores CD4+ T-Cell Recognition

While the defects in HLA class I-mediated Ag presentation by Burkitt lymphoma (BL) have been well documented, CD4+ T-cells are also poorly stimulated by HLA class II Ag presentation, and the reasons underlying this defect(s) have not yet been fully resolved. Here, we show that BL cells are deficient...

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Detalles Bibliográficos
Autores principales: Hossain, Azim, God, Jason M., Radwan, Faisal F. Y., Amria, Shereen, Zhao, Dan, Bethard, Jennifer R., Haque, Azizul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227386/
https://www.ncbi.nlm.nih.gov/pubmed/22162713
http://dx.doi.org/10.1155/2011/780839

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